diff --git a/meta/classes-recipe/cargo_common.bbclass b/meta/classes-recipe/cargo_common.bbclass
index 2e1df9d9d3..37ae729ea6 100644
--- a/meta/classes-recipe/cargo_common.bbclass
+++ b/meta/classes-recipe/cargo_common.bbclass
@@ -51,6 +51,11 @@ CARGO_TARGET_SUBDIR = "${RUST_HOST_SYS}/${BUILD_DIR}"
 # Where we download our registry and dependencies to
 export CARGO_HOME = "${UNPACKDIR}/cargo_home"
 
+# Crates that compile C or assembly sources do so through the cc crate, which
+# is not covered by the rustc specific RUST_DEBUG_REMAP, so map the vendoring
+# directory for the C compiler as well.
+DEBUG_PREFIX_MAP += "-ffile-prefix-map=${CARGO_HOME}=${TARGET_DBGSRC_DIR}"
+
 # Don't instruct cargo to use crates downloaded by bitbake. Some rust packages,
 # for example the rust compiler itself, come with their own vendored sources.
 # Specifying two [source.crates-io] will not work.