diff --git a/meta/classes-recipe/setuptools3.bbclass b/meta/classes-recipe/setuptools3.bbclass
index d71a089539..c4fd30020a 100644
--- a/meta/classes-recipe/setuptools3.bbclass
+++ b/meta/classes-recipe/setuptools3.bbclass
@@ -15,6 +15,9 @@ SETUPTOOLS_SETUP_PATH ?= "${S}"
 setuptools3_do_configure() {
     :
 }
+# This isn't nice, but is the best solutions to ensure clean builds for now.
+# https://github.com/pypa/setuptools/issues/4732
+do_configure[cleandirs] = "${SETUPTOOLS_SETUP_PATH}/build"
 
 setuptools3_do_compile() {
         cd ${SETUPTOOLS_SETUP_PATH}