diff --git a/meta/recipes-devtools/python/python3-packaging/run-ptest b/meta/recipes-devtools/python/python3-packaging/run-ptest
deleted file mode 100644
index 8d2017d39ce..00000000000
--- a/meta/recipes-devtools/python/python3-packaging/run-ptest
+++ /dev/null
@@ -1,3 +0,0 @@
-#!/bin/sh
-
-pytest --automake
diff --git a/meta/recipes-devtools/python/python3-packaging/run-ptest.in b/meta/recipes-devtools/python/python3-packaging/run-ptest.in
new file mode 100644
index 00000000000..508538463bb
--- /dev/null
+++ b/meta/recipes-devtools/python/python3-packaging/run-ptest.in
@@ -0,0 +1,2 @@
+#!/bin/sh
+pytest --automake IGNOREDTESTS
diff --git a/meta/recipes-devtools/python/python3-packaging_24.1.bb b/meta/recipes-devtools/python/python3-packaging_24.1.bb
index 20bcd55fbad..ac8fa4b73f9 100644
--- a/meta/recipes-devtools/python/python3-packaging_24.1.bb
+++ b/meta/recipes-devtools/python/python3-packaging_24.1.bb
@@ -5,7 +5,7 @@ LIC_FILES_CHKSUM = "file://LICENSE;md5=faadaedca9251a90b205c9167578ce91"
 
 SRC_URI[sha256sum] = "026ed72c8ed3fcce5bf8950572258698927fd1dbda10a5e981cdf0ac37f4f002"
 
-SRC_URI += "file://run-ptest"
+SRC_URI += "file://run-ptest.in"
 
 inherit pypi python_flit_core ptest
 
@@ -15,6 +15,9 @@ BBCLASSEXTEND = "native nativesdk"
 DEPENDS:remove:class-native = "python3-build-native"
 RDEPENDS:${PN} += "python3-profile"
 
+SKIPLIST ?= ""
+SKIPLIST:libc-musl = "--deselect tests/test_manylinux.py::test_is_manylinux_compatible_old --ignore=tests/test_tags.py"
+
 do_compile:class-native () {
     python_flit_core_do_manual_build
 }
@@ -23,6 +26,7 @@ do_install_ptest() {
     cp -r ${S}/tests ${D}${PTEST_PATH}/
     # We don't need this script which is used to build the binaries
     rm -f ${D}${PTEST_PATH}/tests/manylinux/build.sh
+    sed -e 's|IGNOREDTESTS|${SKIPLIST}|' ${UNPACKDIR}/run-ptest.in > ${D}${PTEST_PATH}/run-ptest
 }
 
 RDEPENDS:${PN}-ptest = "\