diff --git a/meta/classes-recipe/rust-target-config.bbclass b/meta/classes-recipe/rust-target-config.bbclass
index 2710b4325d..0f72d685df 100644
--- a/meta/classes-recipe/rust-target-config.bbclass
+++ b/meta/classes-recipe/rust-target-config.bbclass
@@ -401,3 +401,20 @@ python do_rust_gen_targets () {
 addtask rust_gen_targets after do_patch before do_compile
 do_rust_gen_targets[dirs] += "${RUST_TARGETS_DIR}"
 
+# For building C dependecies only use compiler parameters defined in OE-core
+# and ignore the default parameters defined in the CC crate.
+# https://github.com/rust-lang/cc-rs#external-configuration-via-environment-variables
+
+# The CC crate checks for CRATE_CC_NO_DEFAULTS existence not value.
+# Even empty CRATE_CC_NO_DEFAULTS will be taken into account.
+# For rust native recipes we still rely on the CC crate parameters.
+# Currently it's not possible to export a variable conditionally,
+# so, let's export it for class-target and class-nativesdk only
+
+do_compile:prepend:class-target() {
+    export CRATE_CC_NO_DEFAULTS=1
+}
+
+do_compile:prepend:class-nativesdk() {
+    export CRATE_CC_NO_DEFAULTS=1
+}